Adrenomedullin as a renal regulator peptide
نویسندگان
چکیده
منابع مشابه
Adrenomedullin as a renal regulator peptide.
belongs to the CGRP superfamily. The human ADM precursor (preproADM) is 185 amino acids in length and is processed to 164-amino acid peptide, proADM, and then to a 52-amino acid peptide, the biologically active form of ADM. The genomic DNA of human
متن کاملAdrenomedullin, an endogenous peptide, counteracts cardiovascular damage.
BACKGROUND Adrenomedullin (AM), a potent vasodilator peptide, is produced by posttranslational splicing of pro-adrenomedullin together with proadrenomedullin N-terminal 20 peptide (PAMP), another hypotensive peptide. Although both AM and PAMP have the potential not only to decrease blood pressure but also to protect organs from damage, there is no direct evidence for their individual physiologi...
متن کاملThe Mammalian Peptide Adrenomedullin Acts as a Growth Factor in Tobacco Plants
Growth factors are extracellular signals that regulate cell proliferation and total body mass. Some animal growth factors can work on plant tissues and vice versa. Here we show that the mammalian growth factor adrenomedullin (AM) induces growth in tobacco plants. Addition of synthetic AM resulted in a dose-dependent growth of tobacco calluses. Furthermore, AM transgenic plants showed enhanced s...
متن کاملAdrenomedullin, a new vasoactive peptide, is increased in preeclampsia.
Adrenomedullin is a novel peptide that elicits a long-lasting vasorelaxant activity. Recently, we found high concentrations of adrenomedullin in maternal and umbilical cord plasma and in amniotic fluid in full-term human pregnancy, indicating a role of this peptide during gestation. To investigate the possibility that adrenomedullin is involved in the pathophysiology of preeclampsia, we measure...
متن کاملAdrenomedullin, a new peptide, in patients with insulinoma.
BACKGROUND It has been demonstrated that adrenomedullin, a newly discovered peptide, affects the release of insulin from pancreatic islets cells, suggesting a role in the insulin-regulating system. OBJECTIVE To investigate whether adrenomedullin secretion is modified in patients with insulin-secreting islet cell tumours. DESIGN The study was performed in nine patients with surgically treate...
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ژورنال
عنوان ژورنال: Nephrology Dialysis Transplantation
سال: 2000
ISSN: 1460-2385,0931-0509
DOI: 10.1093/ndt/15.3.293